自养
同化(音韵学)
生化工程
生物制造
碳同化
范围(计算机科学)
计算机科学
合成生物学
计算生物学
生物
工程类
生物技术
光合作用
生物化学
遗传学
细菌
程序设计语言
语言学
哲学
作者
Xue Yang,Yanfei Zhang,Guoping Zhao
标识
DOI:10.1016/j.biotechadv.2023.108294
摘要
Synthetic biology is being increasingly used to establish novel carbon assimilation pathways and artificial autotrophic strains that can be used in low-carbon biomanufacturing. Currently, artificial pathway design has made significant progress from advocacy to practice within a relatively short span of just over ten years. However, there is still huge scope for exploration of pathway diversity, operational efficiency, and host suitability. The accelerated research process will bring greater opportunities and challenges. In this paper, we provide a comprehensive summary and interpretation of representative one-carbon assimilation pathway designs and artificial autotrophic strain construction work. In addition, we propose some feasible design solutions based on existing research results and patterns to promote the development and application of artificial autotrophy.
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