医学
倾向得分匹配
外科
结直肠癌
减压
造口(药)
支架
临床终点
自膨胀金属支架
回顾性队列研究
入射(几何)
并发症
内科学
癌症
随机对照试验
物理
光学
作者
Koji Numata,Masakatsu Numata,Junya Shirai,Sho Sawazaki,Hironao Okamoto,Teni Godai,Yusuke Katayama,Yosuke Atsumi,Keisuke Kazama,Mamoru Uchiyama,Takashi Kohmura,Hajime Mushiake,Nobuhiro Sugano,Akio Higuchi,Aya Kato,Kenta Iguchi,Yasushi Rino,Manabu Shiozawa
摘要
There are well-known methods for decompressing the colorectal tract before surgery, including transanal decompression tubes (TDT) and self-expanding metallic stents (SEMS). This study aimed to compare the short and long-term results in patients with malignant large bowel obstruction in whom TDT or SEMS were placed before surgery.This retrospective observational study enrolled 225 patients with malignant large bowel obstruction in whom TDT or SEMS were placed preoperatively and underwent R0 resection between 2008 and 2020. One-to-two propensity score matching was performed according to patient characteristics. Short- and long-term outcomes were compared. The primary endpoint was relapse-free survival (RFS). The secondary endpoints were the overall survival (OS) and postoperative complication rate.Fifty-seven patients in the TDT group and 114 in the SEMS group were matched. The 3-year RFS rates were 66.7% in the TDT group and 69.9% in the SEMS group (p = 0.54), and the 3-year OS rates were 90.5% in the TDT group and 87.1% in the SEMS group (p = 0.52). No significant differences in the long-term results were observed between the two groups. Regarding short-term results, the SEMS group had significantly fewer stoma construction (p = 0.007) and shorter postoperative hospitalization (p < 0.001). The incidence of postoperative complications (grade ≥ 2) was significantly lower in the SEMS group (p = 0.04).No significant differences in the long-term results were observed between the TDT and SEMS group. The SEMS showed significant usefulness in terms of improving short-term outcomes.
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