m6A Modification and Implications for microRNAs

Objective: RNA is chemically modified with over 100 distinct reactions. Among these reactions, methylation is probably the most extensively studied modification on the RNA molecule. Studies suggest methylation of Adenine residues (m6A) to be widespread in the transcriptome with potentially important roles in biological processes. Keywords: 3’UTR, m6A, microRNA, mRNA, RNA methylation, transcriptome.