Polyurea elastomers have good physical and chemical properties that can improve the anti-detonation performance when coated on the surface structure. The dynamic response process of polyurea-coated ceramic/steel composite structure under explosive impact is simulated and discussed using ANSYS/LS-DYNA finite element software. The deformation damage, energy absorption, and shock attenuation of single steel plate, steel plate/polyurea, and ceramic/steel plate/polyurea under explosion response were analyzed. The correctness of the simulation is verified by experiments. The results show that the hole size of polyurea coating is smaller than that of a single steel plate structure when polyurea coating is used as a back blasting surface under the same explosion load. The ceramic/steel plate-coated polyurea structure has no obvious cracks and holes, the anti-explosion ability is improved, the energy absorption effect is good, and the shock wave attenuation ability is better than the other two kinds of structures.