计时型
傍晚
睡眠障碍
睡眠(系统调用)
早晨
时间生物学
心理学
睡眠债
医学
全国健康与营养检查调查
昼夜节律
失眠症
人口学
内科学
精神科
人口
环境卫生
天文
社会学
物理
操作系统
计算机科学
作者
Meng Hua Tao,Christopher L. Drake,Chun-Hui Lin
出处
期刊:Sleep Health
[Elsevier]
日期:2024-02-01
卷期号:10 (1): 122-128
标识
DOI:10.1016/j.sleh.2023.11.015
摘要
Abstract
Objective
Sleep is a critical health-related behavior; research evidence has shown that sleep duration, poor sleep quality and insomnia are associated with aging and relevant age-related diseases. However, the associations between sleep duration, chronotype, sleep disturbance, and biological age have not been comprehensively assessed. This study aimed to examine sleep characteristics with biological age. Methods
The study included 6534 participants aged 20 years and older from the National Health and Nutrition Examination Survey between 2017 and March 2020. Sleep questionnaires were used to collect information on sleep duration and wake behavior on workdays and workfree days and sleep disturbance. Phenotypic age acceleration (PhenoAgeAccel) was estimated as a biological age measure using 9 blood chemistry biomarkers. Results
Long sleep (>9 hours) and extremely short sleep (≤4 hours) on workdays were positively associated with PhenoAgeAccel, compared with optimal sleep duration (7-8 hours). Similar positive associations with PhenoAgeAccel were observed for sleep duration on workfree days and across the whole week. Both slightly evening and evening chronotypes were associated with faster PhenoAgeAccel compared to morning chronotype. Social jetlag and sleep disturbance were not associated with PhenoAgeAccel, while long corrected social jetlag was associated with faster PhenoAgeAccel. The associations of sleep duration, chronotype, and corrected social jetlag with PhenoAgeAccel appeared stronger among females than among males. Conclusions
Findings suggest a U-shape relationship between sleep duration and biological aging; slightly evening and evening chronotypes may be risk factors for aging. Further studies are needed to confirm these findings.
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