阿霉素
流出
多重耐药
癌症研究
化疗
癌症
化学
纳米技术
介孔二氧化硅
材料科学
纳米颗粒
抗药性
介孔材料
医学
生物
微生物学
生物化学
内科学
催化作用
作者
Alex M. Chen,Min Zhang,Dongguang Wei,Dirk Stueber,Oleh Taratula,Tamara Minko,Huixin He
出处
期刊:Small
[Wiley]
日期:2009-09-24
卷期号:5 (23): 2673-2677
被引量:635
标识
DOI:10.1002/smll.200900621
摘要
Co-delivery of Doxorubicin and siRNAs by mesoporous silica nanoparticles into multidrug-resistance cancer cells with minimal premature release significantly enhances the efficacy of chemotherapy by conquering the nonpump resistance and possibly bypassing the efflux pump resistance (see image). Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
科研通智能强力驱动
Strongly Powered by AbleSci AI