医学
恶性肿瘤
疾病
随机对照试验
新辅助治疗
辅助治疗
外科
肿瘤科
普通外科
内科学
癌症
化疗
乳腺癌
作者
Rachel Lee,Shishir K. Maithel
标识
DOI:10.1016/j.soc.2019.06.014
摘要
Distal cholangiocarcinoma is a rare malignancy with a dismal prognosis. Because of its location and aggressive nature, patients often present with locally advanced or metastatic disease, and effective treatment options are limited. For patients with resectable disease, surgery is the only chance for cure, but achieving an R0 resection is paramount. Optimal adjuvant therapy in resectable disease remains under investigation. Randomized controlled trials investigating neoadjuvant therapy and its impact on resectability and long-term outcomes are needed to continue to improve the outcomes of patients with distal cholangiocarcinoma.
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