P3-110: Neuropsychiatric symptoms in amnestic and nonamnestic mild cognitive impairment

The information regarding neuropsychiatric symptoms in the subtypes of mild cognitive impairment (MCI) is inadequate. To describe the behavioral neuropsychiatric symptoms of MCI in two subgroups of MCI patients with different neuropsychological characteristics. MCI patients are classified as amnestic (aMCI) if they have a prominent memory impairment, either alone or with other cognitive impairments (multiple domains with amnesia), or nonamnestic (naMCI) if a single nonmemory domain is impaired alone or in combination with other nonmemory deficits (multiple domains without amnesia). The K-Neuropsychiatric Inventory (NPI) was administrated to detect behavioral and psychological disturbances observed by the caregiver. 58 subjects were analyzed: 43 were classified as aMCI and 15 as naMCI. About 76% of MCI patients had some neuropsychiatric symptoms evaluated with the NPI and the most prevalent symptom was depression, followed by anxiety & apathy. A significantly higher prevalence of hallucinations has been observed in the naMCI group in comparison with the aMCI group. Neuropsychiatric symptoms occur in the majority of persons with MCI. A significantly higher prevalence of hallucinations has been observed in the naMCI group in comparision with the aMCI group. Neuropsychological & behavioral assessment is considered as an importment step in the categorization of subjects with MCI.