Facile Preparation of ZIF-8 MOF Coated Mesoporous Magnetic Nanoarticles to Provide a Magnetic Solid Phase Extraction Platform

In this work, zeolitic imidazolate framework (ZIF-8) coated mesoporous magnetic nanoparticles (Fe3O4@PDA@mSiO2@ZIF-8) were prepared through a facile and efficient strategy and used as a magnetic solid phase extraction platform for phthalates detection. Polydopamine (PDA) not only provides a hydrophilic layer, but also possesses π electrons for aromatic compounds recognition; mSiO2 endows the nanoparticles with large surface area and regular channels, which facilitates the rapid transport of phthalates. The prepared Fe3O4@PDA@mSiO2@ZIF-8 with imposed properties showed ultrahigh efficiency and reusability for phthalates determination in human plasma samples. The linearity range was 50–8000 ng/mL, limits of detection were between 50–80 ng/mL, the intra-day RSDs were lower than 4.8%, inter-day RSDs were lower than 6.7%, the recoveries ranged from 90 to 107%. The new prepared nanoparticles displayed potential performance for aromatic compounds detection.