动物福利
协议(科学)
工程伦理学
动物试验
传播
主题(文档)
研究伦理
基础(证据)
实验研究
管理科学
计算机科学
心理学
医学教育
医学
替代医学
政治学
病理
生物
数学教育
工程类
法学
图书馆学
电信
生态学
作者
Lorenza Dı́az,Elena Zambrano,María Elena Flores,Mariela Contreras,José C. Crispín,Gabriela Alemán,César Bernal Bravo,Alejandra Armenta,Victor J. Valdés,Armando R. Tovar,Gerardo Gamba,Jorge Barrios-Payán,Norma A. Bobadilla
标识
DOI:10.24875/ric.20000380
摘要
In the last century, progress in the knowledge of human diseases, their diagnosis and treatment have grown exponentially, due in large part to the introduction and use of laboratory animals. Along with this important progress, the need to provide training and guidance to the scientific community in all aspects related to the proper use of experimental animals has been indispensable. Animal research committees play a primary role in evaluating experimental research protocols, from their feasibility to the rational use of animals, but above all in seeking animal welfare. The Institutional Committee for the Care and Use of Animals (IACUC) has endeavored to share several relevant aspects in conducting research with laboratory animals. Here, we present and discuss the topics that we consider of utmost importance to take in the account during the design of any experimental research protocol, so we invite researchers, technicians, and undergraduate and graduate students to dive into the fascinating subject of proper animal care and use for experimentation. The main intention of these contributions is to sensitize users of laboratory animals for the proper and rational use of them in experimental research, as well as to disseminate the permitted and unpermitted procedures in laboratory animals. In the first part, the significance of experimental research, the main functions of IACUC, and the principle of the three R's (replacement, reduction, and refinement) are addressed.
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