再灌注损伤
心脏病学
心肌再灌注损伤
缺血
医学
心肌缺血
内科学
作者
Anna Roslan,Katharina Paulus,Jiaqi Yang,Lucas Matt,Helmut Bischof,Natalie Längst,Sophia Schanz,Annika Luczak,Melanie Cruz Santos,Sandra Burgstaller,David Skrabak,Nadja I. Bork,Roland Malli,Achim Schmidtko,Meinrad Gawaz,Viacheslav O. Nikolaev,Peter Ruth,Rebekka Ehinger,Robert Łukowski
摘要
Collectively, our study provides evidence for Slack's crucial involvement in the ion homeostasis of no or low O2-stressed CMs. Thereby, Slack activity opposes the I/R-induced fatal Ca2+-uptake to CMs supporting the cardioprotective signaling attributed to mitoKATP function.
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(2025-6-4)
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