分解代谢
内科学
内分泌学
银屑病
炎症
过氧化物酶体增殖物激活受体
缬氨酸
下调和上调
化学
氨基酸
受体
生物
新陈代谢
医学
免疫学
基因
生物化学
作者
Yazhuo Wang,Ning Zhao,Yujiao Meng,Jia Chen,Cong Qi,Xueqing Hu,Haoyue Zhu,Danyang Yang,Xiawei Zhang,Huike Ma,Jingxia Zhao,Tingting Di,Ping Li,Yan Wang,Yan Wang,Yan Wang
标识
DOI：10.1002/mnfr.202300720
摘要
HFD-induced obesity significantly amplifies IL-17 signaling and exacerbates psoriasis, with a potential role played by Bcat2-mediated BCAAs metabolism. The study suggests that BCAA catabolism and PPAR γ-STAT3 exacerbate inflammation in psoriasis with obesity.
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(2025-6-4)
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