化学
钳子运动
钯
苯硼酸
芳基
恶唑啉
配体(生物化学)
药物化学
钳形配体
有机化学
催化作用
生物化学
受体
烷基
作者
Xin‐Qi Hao,Yanan Wang,Jun‐Rui Liu,Kunlun Wang,Jun‐Fang Gong,Mao‐Ping Song
标识
DOI:10.1016/j.jorganchem.2009.09.031
摘要
The unsymmetrical, achiral and chiral NCN pincer ligand precursors (3a-3d) with oxazoline and pyrazole as N donors as well as (3e) which has oxazolinyl and amino group have been synthesized in a facile manner in four steps starting from commercially available isophthalaldehyde. Direct C2 metallation of the precursors (3a–3e) with Pd(OAc)2 in refluxing HOAc, followed by treatment with LiCl at room temperature provided convenient access to the corresponding pincer palladium(II) complexes (4a–4e). The molecular structure of complex 4e has been determined by X-ray single-crystal diffraction. The obtained Pd complexes exhibited good activities in the Suzuki reactions of aryl bromides and activated aryl chlorides with phenylboronic acid.
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