医学
钙化
血管成形术
放射科
股动脉
外围设备
股浅动脉
气球
内科学
心脏病学
血管疾病
动脉疾病
作者
Shinsuke Mori,Mitsuyoshi Takahara,Tatsuya Nakama,Kazuki Tobita,Naoki Hayakawa,Yusuke Iwata,Kazunori Horie,Kenji Suzuki,Masahiro Yamawaki,Yoshiaki Ito
摘要
Abstract Purpose To investigate whether the severity of calcification assessed by the peripheral artery calcification scoring system (PACSS) was associated with clinical outcomes of drug‐coated balloon (DCB) angioplasty for femoropopliteal lesions. Materials and Methods We retrospectively analyzed 733 limbs with intermittent claudication of 626 patients, who underwent DCB angioplasty for de novo femoropopliteal lesions between January 2017 and February 2021 at seven cardiovascular centers in Japan. The patients were categorized using the PACSS classification (grades 0–4: no visible calcification of the target lesion, unilateral wall calcification < 5 cm, unilateral calcification ≥ 5 cm, bilateral wall calcification < 5 cm, and bilateral calcification ≥ 5 cm, respectively). The main outcome was primary patency at 1 year. The Cox proportional hazards analysis was used to explore whether the PACSS classification was an independent predictor of clinical outcomes. Results The distribution of PACSS was grade 0 in 38%, grade 1 in 17%, grade 2 in 7%, grade 3 in 16%, and grade 4 in 23%. The 1‐year primary patency rates in these grades, respectively, were 88.2%, 89.3%, 71.9%, 96.5%, and 82.6%, respectively ( p < 0.001). Multivariate analysis disclosed that PACSS grade 4 (hazard ratio: 1.82, 95% confidence interval 1.15−2.87, p = 0.010) was associated with restenosis. Conclusion The PACSS grade 4 calcification was independently associated with poor clinical outcomes after DCB angioplasty for de novo femoropopliteal lesions.
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