适体
生物信息学
药物输送
靶向给药
计算生物学
计算机科学
药品
生化工程
纳米技术
风险分析(工程)
医学
生物
药理学
工程类
基因
材料科学
生物化学
遗传学
作者
Biagio Todaro,Elisa Ottalagana,Stefano Luin,Melissa Santi
出处
期刊:Pharmaceutics
[MDPI AG]
日期:2023-06-03
卷期号:15 (6): 1648-1648
被引量:1
标识
DOI:10.3390/pharmaceutics15061648
摘要
Peptides can act as targeting molecules, analogously to oligonucleotide aptamers and antibodies. They are particularly efficient in terms of production and stability in physiological environments; in recent years, they have been increasingly studied as targeting agents for several diseases, from tumors to central nervous system disorders, also thanks to the ability of some of them to cross the blood-brain barrier. In this review, we will describe the techniques employed for their experimental and in silico design, as well as their possible applications. We will also discuss advancements in their formulation and chemical modifications that make them even more stable and effective. Finally, we will discuss how their use could effectively help to overcome various physiological problems and improve existing treatments.
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