化学
三氟甲基化
丁基羟基甲苯
产量(工程)
循环伏安法
电化学
芳基
激进的
催化作用
加合物
有机化学
组合化学
光化学
抗氧化剂
三氟甲基
电极
冶金
材料科学
物理化学
烷基
作者
Chunzhao Xu,Yue Liu,Hao Líu,Junjie Ma,Xin He,Hongfeng Wu,Yuqin Li,Zheng Sun,W. K. Chu
标识
DOI:10.1016/j.tetlet.2020.152226
摘要
Electrochemical direct trifluoromethylation of quinolinones was described under metal-free catalysis and oxidant-free conditions. A series of 2-aryl-3-trifluoromethylquinoline-4(1H)-ones were obtained in medium to good yield by using the method. By using butylated hydroxytoluene (BHT) as free radical blocker, adduct of BHT-CF3 was originally captured, which confirmed that the reaction was a free radical mechanism. Based on the results of capturing radical and cyclic voltammetry (CV), a reaction mechanism was proposed.
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