生物炭
萃取(化学)
热解
竹子
色谱法
固相萃取
碳化
固相微萃取
竹炭
吸附
解吸
化学
磁性纳米粒子
质谱法
材料科学
气相色谱-质谱法
纤维
有机化学
纳米颗粒
纳米技术
复合材料
作者
Suling Zhang,Ziluo Hua,Weixuan Yao,Ting Lü,Dong Zhang,Qingwei Zhao,Jianhong Li,Hongting Zhao
标识
DOI:10.1002/jssc.202200049
摘要
In this study, a biochar-based magnetic solid-phase microextraction method, coupled with liquid chromatography-mass spectrometry, was developed for analyzing fentanyl analogs from urine sample. Magnetic biochar was fabricated through a one-step pyrolysis carbonization and magnetization process, followed by an alkali treatment. In order to achieve desired extraction efficiency, feed stocks (wood and bamboo) and different pyrolysis temperatures (300-700°C) were optimized. The magnetic bamboo biochar pyrolyzed at 400°C was found to have the greatest potential for extraction of fentanyls, with enrichment factors ranging from 58.9 to 93.7, presumably due to H-bonding and π-π interactions between biochar and fentanyls. Various extraction parameters, such as type and volume of desorption solvent, pH, and extraction time, were optimized, respectively, to achieve the highest extraction efficiency for the target fentanyls. Under optimized conditions, the developed method was found to have detection limits of 3.0-9.4 ng/L, a linear range of 0.05-10 μg/L, good precisions (1.9-9.4% for intrabatch, 2.9-9.9% for interbatch), and satisfactory recoveries (82.0-111.3%). The developed method by using magnetic bamboo biochar as adsorbent exhibited to be an efficient and promising pretreatment procedure and could potentially be applied for drug analysis in biological samples.
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