心理学
认知
精神病
听力学
言语记忆
执行功能障碍
神经心理学
蒙特利尔认知评估
认知缺陷
语言学习
精神分裂症(面向对象编程)
认知测验
视觉记忆
帕金森病
记忆广度
执行职能
精神科
临床心理学
作者
Abhishek Lenka,Shantala Hegde,Shyam Sundar Arumugham,Puneet Singh,Ravi Yadav,PramodKumar Pal
出处
期刊:Canadian Journal of Neurological Sciences
[Cambridge University Press]
日期:2021-12-13
卷期号:: 1-15
摘要
Psychosis is one of the incapacitating nonmotor symptoms of Parkinson's disease (PD). Although several risk factors that include older age, rapid eye movement sleep behavior disorder, depression, and cognitive dysfunction have been identified, the exact neural correlates remain elusive. As cognitive impairment has a close association with psychosis in PD, it is useful to know the spectrum of cognitive impairment in PD patients with psychosis (PD-P).This cross-sectional study compared various cognitive parameters of PD-P (visual/minor hallucinations) and PD patients with no psychosis (PD-NP). A neuropsychological battery encapsulating several cognitive domains (executive, visuospatial, learning, and memory) was used for the cognitive assessment of 37 PD-P and 51 PD-NP patients who were matched for age, gender, education, and disease duration.The two groups were comparable in terms of disease severity and stage. Although the groups had a comparable mean score on Montreal cognitive assessment, the PD-P group performed poorly in tests focused on executive function (color trail test, forward digit span), verbal learning and memory (Rey auditory and verbal learning test), and visuospatial functions (complex figure test, corsi block tapping test). Those with complex visual hallucinations performed poorly in the color trial test (part A) compared to those with minor hallucinations.Psychosis is associated with a multidomain cognitive dysfunction in PD. All PD patients should undergo detailed cognitive assessment as cognitive dysfunction may be a marker of psychosis in the future. Additional longitudinal studies are warranted to obtain detailed insights into this issue.
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