化学
苯并咪唑
喹啉
吡啶
催化作用
齿合度
配体(生物化学)
嘧啶
组合化学
磷化氢
基础(拓扑)
立体化学
药物化学
有机化学
晶体结构
受体
数学分析
生物化学
数学
作者
S. K. Nandi,Ishani Borthakur,Kasturi Ganguli,Sabuj Kundu
出处
期刊:Organometallics
[American Chemical Society]
日期:2023-05-11
卷期号:42 (14): 1793-1802
被引量:3
标识
DOI:10.1021/acs.organomet.3c00034
摘要
A series of phosphine-free benzimidazole and pyridine-containing bidentate Mn(I) complexes were synthesized. Among them, Mn1 complex bearing a proton-responsive 2-hydroxypyridine-appended benzimidazole ligand was found to be highly effective for the synthesis of different N-heterocycles utilizing alcohols. Employing significantly lower catalyst loading (0.05 mol %), several substituted pyrimidines and quinolines were effectively synthesized. The lactim–lactam acid–base equilibrium of the 2-hydroxypyridine fragment, role of the countercation of the base, and effect of the externally added ligands were investigated. A probable catalytic cycle was proposed based on the basis of various control experiments and different kinetic studies.
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