杜皮鲁玛
医学
大疱性类天疱疮
皮肤病科
回顾性队列研究
类天疱疮
耐火材料(行星科学)
效力
内科学
特应性皮炎
免疫学
抗体
体外
化学
物理
天体生物学
生物化学
作者
Parna Moghadam,Emmanuelle Tancrède‐Bohin,Jean‐David Bouaziz,Julien Kallout,C. Bédane,É. Bégon,Isabelle Bourgault‐Villada,A. Calugareanu,O. Dereure,Fatma Jendoubi,Anne Pham‐Ledard,S. Oro,C. Picard‐Dahan,M. Viguier,T. Mahévas,M. Jachiet,Estelle Charvet,C. Cassius,M. Alexandre,C. Lepelletier
摘要
Bullous pemphigoid (BP) is the most common autoimmune blistering disease in Europe and its treatment can be challenging. Several published cases have reported dupilumab efficiency in treatment-refractory patients. We conducted a retrospective multicentric study of 36 patients to evaluate the real-life efficiency of dupilumab in BP. Our results suggest that dupilumab, in association with high-potency topical steroids, could be rapidly effective in various clinical forms of BP and seems to be well tolerated in the elderly.
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