阴道加德纳菌
医学
奥硝唑
舒巴坦钠
头孢哌酮
厌氧菌
头孢菌素
微生物学
内科学
胃肠病学
抗生素
细菌性阴道病
妇科
细菌
抗生素耐药性
生物
遗传学
亚胺培南
作者
Yu Mu,Jingjing Li,Wei Xiao,Xin-Fang Zhou,Lian Tang,Qin Zhou
出处
期刊:World Journal of Clinical Cases
[Baishideng Publishing Group Co (World Journal of Clinical Cases)]
日期:2022-09-16
卷期号:10 (26): 9323-9331
标识
DOI:10.12998/wjcc.v10.i26.9323
摘要
Gardnerella vaginalis (G. vaginalis) is a facultative anaerobic bacteria known to cause bloodstream infections. However, cases are very rare in clinics. There is very limited clinical experience in the treatment of bloodstream infections caused by G. vaginalis. Therefore, there is an urgent need for effective antibacterial drugs to treat patients with bloodstream infections caused by G. vaginalis.A woman who underwent a cesarean section presented with a sudden onset of high fever 1-d post-surgery. The blood cultures suggested an infection due to G. vaginalis, and treatment with cefoperazone-sulbactam was started. After 5 d of treatment, there was a decrease in the hemogram; however, the temperature and C-reactive protein levels remained high. Based on clinical experience and a review of literature, the treatment was modified to include ornidazole in combination with cefoperazone-sulbactam. Following a week of treatment, the temperature, hemogram and C-reactive protein levels returned to normal, and blood cultures turned negative, suggesting a therapeutic effect of the combination treatment.This case highlighted the effective use of cefoperazone-sulbactam combined with ornidazole for bloodstream infection caused by G. vaginalis following a cesarean section.
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