微量白蛋白尿
医学
糖尿病性视网膜病变
视网膜病变
视力
眼科
糖尿病
2型糖尿病
对比度(视觉)
眼底摄影
检眼镜
眼底(子宫)
内科学
荧光血管造影
内分泌学
视网膜
人工智能
计算机科学
作者
Hans‐Jacob Bangstad,Olaf Brinchmann‐Hansen,Staale J. Hultgren,Knut Dahl‐Jørgensen,K. F. Hanssen
标识
DOI:10.1111/j.1755-3768.1994.tb04677.x
摘要
Abstract. We compared neurosensorial visual function by psychophysical tests (macular recovery time and contrast sensitivity) in two well matched groups of young Type 1 (insulin‐dependent) diabetic patients with micro‐and normoalbuminuria, respectively. The patients had normal visual acuity (≥ 1.0) and either no retinopathy or non‐proliferative retinopathy. Thirty patients with microalbuminuria (albumin excretion ≥ 15 μg/min in a least two out of three timed overnight urine samples) were matched (age, diabetes duration, mean one‐year HbA 1c , gender) with normoalbuminuric (n = 27) patients. Retinopathy (50° colour fundus photography) was assessed by counting microaneurysms and hemorrhages as ‘red spots’. Contrast sensitivity was examined for the spatial frequencies of 1.5, 3, 6, 12 and 18 cycles per degree (cpd). Macular recovery time (nyctometry) refers to the time‐related (2 min) ability of the retina to regain visual acuity following exposure to bright light (photostress). Contrast sensitivity score was reduced in patients with microalbuminuria compared to those without; 18 cpd (mean and 95% confidence intervals): [4.2 (3.8‐4.7) vs 5.0 (4.6‐5.4), p = 0.03]. Macular recovery performance was not significantly reduced: [21.0 arbitrary units (17.5–24.6) vs 26.0 (22.6–30.7), p = 0.12]. We conclude that impaired contrast sensitivity independent of background retinopathy is shown in a group of young Type 1 (insulin‐dependent) diabetic patients with low‐grade microalbuminuria compared to a group of patients with normoalbuminuria.
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