医学
前列腺癌
前列腺特异性抗原
指南
前列腺癌筛查
随机对照试验
癌症
前列腺
肿瘤科
妇科
临床试验
内科学
病理
作者
Kari A.O. Tikkinen,Philipp Dahm,Lyubov Lytvyn,Anja Fog Heen,Robin W.M. Vernooij,Reed Siemieniuk,Russell Wheeler,Bill Vaughan,Awah Cletus Fobuzi,Marco H. Blanker,Noelle Perron Junod,Johanna Sommer,Jérôme Stirnemann,Manabu Yoshimura,Reto Auer,Helen Macdonald,Gordon Guyatt,Per Olav Vandvik,Thomas Agoritsas
出处
期刊:BMJ
[BMJ]
日期:2018-09-05
卷期号:: k3581-k3581
被引量:102
摘要
### What you need to know What is the role of prostate-specific antigen (PSA) screening in prostate cancer? An expert panel produced these recommendations based on a linked systematic review.1 The review was triggered by a large scale, cluster randomised trial on PSA screening in men without a previous diagnosis of prostate cancer published in 2018 (box 1).2 It found no difference between one-time PSA screening and standard practice in prostate cancer mortality but found an increase in the detection of low risk prostate cancer after a median follow-up of 10 years. Box 1 ### Results of the CAP Randomized Clinical Trial2 This cluster-randomised trial of 419 582 British men was published in March 2018. After a median follow-up of 10 years, there was no significant difference in prostate cancer-specific mortality in men receiving care by general practices randomised to a single PSA screening intervention compared with men receiving care … RETURN TO TEXT
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