牙本质形成
动物模型
臼齿
牙髓(牙)
体内
生物
牙科
成牙本质细胞
医学
遗传学
内分泌学
作者
Rebecca Babb,Dhivya Chandrasekaran,Lucia K. Zaugg,Paul T. Sharpe
标识
DOI:10.1007/978-1-4939-9012-2_11
摘要
Different animal models have been introduced recently to study the process of reparative dentinogenesis in response to injury-induced pulp exposure. Using a mouse model is advantageous over other animal models since mice can be genetically manipulated to examine specific cellular pathways and lineage trace the progeny of a single cell. However, enabling a standardized molar damage in mice is demanding due to the small size of the teeth compared to the available dental instruments. Here we describe a reproducible and reliable in vivo model that allows us to study dentinogenesis in the first maxillary mouse molar.
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