[Intra-articular injections of hyaluronic acid for anterior disc displacement of temporomandibular joint].

Anterior disc displacement (ADD) of temporomandibular joint (TMJ) is regarded as one of the major findings in temporomandibular disorders (TMD). It is related to joint noise, pain, mandibular dysfunction, degenerative change and osteoarthritis. In the mean time, the pathological changes were found in synovial membrane and synovial fluid. Hyaluronic acid is a principal component of the synovial fluid which plays an important role in nutrition, lubrication, anti-inflammation and cartilage repair. The synthesis, molecule weight, and concentration of hyaluronic acid are decreased during TMD and cause TMJ degenerative changes. The clinical conditions, pathological changes, the mechanism of action for hyaluronic acid and the treatment of anterior disc displacement of TMJ are discussed in this article.颞下颌关节盘前移位在颞下颌关节紊乱病中很常见，可导致关节弹响、疼痛、下颌功能障碍以及骨关节炎，同时关节滑膜与滑液也出现病理性改变。透明质酸是关节滑液的主要成分，其主要作用为营养关节软骨、维持关节正常的润滑、抗炎功能以及软骨修复。发生颞下颌关节紊乱病时，透明质酸的合成、相对分子质量、浓度均下降，导致关节发生退行性改变。本文就颞下颌关节盘前移位的临床表现、病理改变、透明质酸作用机制以及临床应用等方面进行介绍。.