Purpose To introduce the design and fabrication of two types of cyst plugs and their application in drainage following marsupialization of jaw cysts. Methods The clasp-retained cyst plugs were classified into two types, conventional and denture-like type according to their different function, and steps and procedures for making cyst plugs were described respectively. Results Cyst plugs were used for 32 lesions in molar regions, 7 in premolar and 4 in anterior regions. There were 35 conventional and 8 denture-like types, which kept cyst opening unobstructed in all patients without complications associated with these devices. Conclusions The clasp-retained cyst plug is a better drainage device for marsupialized jaw cysts and denture-like type can temporarily replace the lost tooth postoperatively.