[Research progress on mosaic embryo transfer and pregnancy risk].

Mosaic embryos contain two or more genetically distinct cell lines, which can be detected by pre-implantation genetic testing for aneuploidy. At present, it has been reported that mosaic embryo transfer can lead to healthy live births. In order to prevent severe adverse pregnancy outcomes, such as implantation failure, abortion, congenital malformation and neonatal death after implantation of mosaic embryos, it is critical to carry out genetic counseling, prenatal diagnosis and pregnancy supervision for mosaic embryo transfer. This article reviews the selection of mosaic embryos, the pregnancy outcomes of mosaic embryo transfer, and the safety of offspring, in order to provide references for the clinical practice of mosaic embryo transfer.嵌合体胚胎是指含有两种或多种遗传学不同的细胞系的胚胎，常在胚胎植入前非整倍体检测中发现。目前已有报道嵌合体胚胎移植后可获得健康活产。为预防植入失败、流产、先天性畸形及新生儿死亡等严重不良妊娠结果，针对嵌合体胚胎移植开展遗传咨询、产前诊断及妊娠监督十分关键。本文从嵌合体胚胎的选择、嵌合体胚胎移植的妊娠结局及子代安全性等方面进行综述，以期为嵌合体胚胎移植的临床实践提供参考意见。.