Water-Insoluble Drug Formulation, Third Edition

Introduction, R. Liu Solubility Theories, S.H. Neau Prediction of Solubility, Y. Chen, X. Oi, and R. Liu Preformulation Aspects of Insoluble Compounds, W.Q. Tong and H. Zhou Water-Insoluble Drugs and their Pharmacokinetic Behaviors, H. Zhou Regulatory Aspects of Dissolution for Low Solubility Drug Products, P. Sathe, R.A. Lionberger, and LX.. Yu Formulation Strategies and Practice Used for Drug Candidates with Water-Insoluble Properties for Toxicology, Biology, and Pharmacology Studies in Discovery Support, L.-F. Huang and J. Dong Applications of Complexation in the Formulation of Insoluble Compounds, W.-Q. Tong and H. Wen Solubilization Using CoSolvent Approach, J.S. Trivedi Emulsions, Microemulsions, and Lipid-based Drug Delivery Systems for Drug Solubilization and Delivery, Part I: Parenteral Applications, J.B. Cannon, Y. Shi, and P. Gupta Emulsions, Microemulsions, and Lipid-based Drug Delivery Systems for Drug Solubilization and Delivery, Part II: Oral Applications, J.B. Cannon and M.A. Long Micellization and Drug Solubility Enhancement, R. Liu and R.-M. Dannenfelser, and S. Li Micellization and Drug Solubility Enhancement Part II: Polymeric Micelles, R. Liu, M.L. Forrest, and G.S. Kwon Liposomes in Solubilization, R. Liu, J.B. Cannon, and Y.S. Paspal Pharmaceutical Salts, S.H. Neau Prodrugs for Improved Aqueous Solubility, S.H. Neau Particle Size Reduction, R.W. Lee, J.M. Shaw, J. McShane, R.W. Wood, and D.B. Shenoy Development of Solid Dispersions for Poorly Water-Soluble Drugs, M. Vasanthavada, W.-Q. Tong, and A. Serajuddin Alternation of the Solid State of the Drug Substances: Polymorphs, Solvates, and Amorphous Forms, P. Myrdal and M.J. Jozwiakowski Pharmaceutical Powder Technology - Building the Pyramid of Knowledge and the Challenge of FDA's PAT Initiative, H. Leuenberger and G. Betz Soft Gelatin Capsules Development, E. Tabibi and S.L. Gupta Oral Modified-Release Drug Delivery for Water-Insoluble Drugs, S. Li, N. Wang, and R. Liu Scalable Manufacturing of Water-Insoluble Drug Products, N. Pathak and R. Huang Drug Products, N. Pathak and R. Huang