Effects and side‐effects of tranexamic acid: they both matter

医学 氨甲环酸 图书馆学 引用 外科 计算机科学 失血
作者
Seema Agarwal,M. Heesen
出处
期刊:Anaesthesia [Wiley]
卷期号:78 (11): 1320-1322
标识
DOI:10.1111/anae.16089
摘要

AnaesthesiaEarly View Editorial Effects and side-effects of tranexamic acid: they both matter S. Agarwal, Corresponding Author S. Agarwal Consultant, Honorary Senior Lecturer [email protected] orcid.org/0000-0002-9991-507X @@seemamosca Department of Anaesthesia, Manchester University Hospitals, Manchester, UK Manchester University, Manchester, UK Correspondence to: S. Agarwal Email: [email protected]Search for more papers by this authorM. Heesen, M. Heesen Consultant Department of Anaesthesia, Kantonsspital Baden, Baden, SwitzerlandSearch for more papers by this author S. Agarwal, Corresponding Author S. Agarwal Consultant, Honorary Senior Lecturer [email protected] orcid.org/0000-0002-9991-507X @@seemamosca Department of Anaesthesia, Manchester University Hospitals, Manchester, UK Manchester University, Manchester, UK Correspondence to: S. Agarwal Email: [email protected]Search for more papers by this authorM. Heesen, M. Heesen Consultant Department of Anaesthesia, Kantonsspital Baden, Baden, SwitzerlandSearch for more papers by this author First published: 07 July 2023 https://doi.org/10.1111/anae.16089 1 Consultant, Department of Anaesthesia, Manchester University Hospitals, Manchester, UK 2 Honorary Senior Lecturer, Manchester University, Manchester, UK 3 Consultant, Department of Anaesthesia, Kantonsspital Baden, Baden, Switzerland This editorial accompanies an article by Tsan et al., Anaesthesia 2023; https://doi.org/10.1111/anae.16058. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1 National Confidential Enquiry into Patient Outcome and Death. Knowing the risk: a review of the peri-operative care of surgical patients. 2011. https://www.ncepod.org.uk/2011report2/downloads/POC_summary.pdf (accessed 15/05/2023). 2Abbott TEF, Fowler AJ, Dobbs TD, Harrison EM, Gillies MA, Pearse RM. Frequency of surgical treatment and related hospital procedures in the UK: a national ecological study using hospital episode statistics. British Journal of Anaesthesia 2017; 119: 249–57. 3 Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators. Association between complications and death within 30 days after noncardiac surgery. Canadian Medical Association Journal 2019; 191: E830–7. 4Devereaux PJ, Marcucci M, Painter TW, et al. Tranexamic acid in patients undergoing noncardiac surgery. New England Journal of Medicine 2022; 386: 1986–97. 5 CRASH-2 Trial Collaborators et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376: 23–32. 6 WOMAN Trial Collaborators. Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet 2017; 389: 2105–16. 7 Royal College of Surgeons of England. Tranexamic acid to reduce surgical bleeding. 2022. https://www.rcseng.ac.uk/news-and-events/news/archive/tranexamic-acid-to-reduce-surgical-bleeding (accessed 02/05/2023). 8 NHS Blood and Transport. 2021 National Comparative Audit of NICE Quality Standard QS138. 2022 https://hospital.blood.co.uk/audits/national-comparative-audit/reports-grouped-by-year/2021-national-comparative-audit-of-nice-quality-standard-qs138/ (accessed 02/05/2023). 9Myles PS, Smith JA, Forbes A, et al. Tranexamic acid in patients undergoing coronary artery surgery. New England Journal of Medicine 2017; 376: 136–48. 10Tsan SEH, Viknaswaran NL, Cheong CC, et al. Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis. Anaesthesia 2023. Epub 14 June. https://doi.org/10.1111/anae.16058. 11Bramley P, Wiles MD. How to perform and write a meta-analysis. Anaesthesia 2022; 77: 1299–303. 12Choi SW, Lam DM. Trials and tribulations of a meta-analyst. Anaesthesia 2016; 71: 228–31. 13Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. British Medical Journal 2021; 372: n71. 14Heesen M, Klimek M, Hoeks SE. Restrictive or responsive? Outcome classification and unplanned sub-group analyses in meta-analyses. Anaesthesia 2018; 73: 279–83. 15Sterne JAC, Savović J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. British Medical Journal 2019; 366: l4898. 16Shah A, Smith AF. Trial sequential analysis: adding a new dimension to meta-analysis. Anaesthesia 2020; 75: 15–20. 17Clephas PRD, Kranke P, Heesen M. How to perform and write a trial sequential analysis. Anaesthesia 2023; 78: 381–4. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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