医学
纤维瘤病
侵袭性纤维瘤病
低温消融
外科
阿霉素
放射科
化疗
内科学
烧蚀
作者
Katherine Prendergast,Sara Kryeziu,Aimeé M. Crago
标识
DOI:10.1016/j.suc.2022.05.005
摘要
Desmoid fibromatosis is a rare disease caused by genetic alterations that activate β-catenin. The tumors were previously treated with aggressive surgeries but do not metastasize and may regress spontaneously. For these reasons, in the absence of symptoms and when growth would not induce significant complications, active observation is considered first-line therapy. When intervention is required, surgery can be considered based on anatomy and risk of postoperative recurrence, but increasingly nonoperative therapies such as liposomal doxorubicin or sorafenib are prescribed. Cryoablation, chemoembolization, and high-intensity focused ultrasound can also be used to obtain local control in selected patients.
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