医学
社会心理的
糖尿病
2型糖尿病
性别特征
流行病学
1型糖尿病
内科学
内分泌学
精神科
作者
Giuseppina T. Russo,Valeria Manicardi,Maria Chiara Rossi,Emanuela Orsi,Anna Solini
标识
DOI:10.1016/j.numecd.2022.08.011
摘要
AimsThis review summarizes the contribution of Italian diabetologists devoted to a better understanding of the complex relationship linking sex/gender and long-term complications of type 1 (T1DM) and type 2 diabetes (T2DM) over the last fifteen years.Data synthesisMicrovascular and macrovascular complications of diabetes show sex- and gender-related differences, involving pathophysiological mechanisms, epidemiological features and clinical presentation, due to the interaction between biological and psychosocial factors. These differences greatly impact on the progression of diabetes and its long-term complications, especially in the cardiovascular, renal and liver districts.ConclusionA better knowledge of such sex- and gender-related characteristics is required for a more precise patient phenotypization, and for the choice of a personalized antihyperglycemic treatment. Despite such mounting evidence, current diabetes clinical guidelines do not as yet adequately consider sex/gender differences.
科研通智能强力驱动
Strongly Powered by AbleSci AI