医学
糖尿病性视网膜病变
2型糖尿病
生活质量(医疗保健)
视力
视网膜病变
糖尿病
人口
队列研究
老年学
验光服务
眼科
内科学
内分泌学
环境卫生
护理部
作者
Flávio E. Hirai,James M. Tielsch,Barbara E.K. Klein,Ronald Klein
出处
期刊:Ophthalmology
[Elsevier]
日期:2011-02-01
卷期号:118 (2): 353-358
被引量:67
标识
DOI:10.1016/j.ophtha.2010.06.022
摘要
To investigate changes of vision-related quality of life during a 10-year period in a population with type 1 diabetes.Prospective cohort study.Individuals who had their diabetes diagnosed before 30 years of age were considered to have type 1 diabetes (N = 1210). Those who participated in both 14-year (1995-1996) and 25-year (2005-2007) follow-up examinations were included in the current analysis (N = 471).Vision-related quality of life was measured with the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25).Changes in vision-related quality of life scores.Loss of 3 lines in the Early Treatment Diabetic Retinopathy Study (ETDRS) chart was the most important factor related to negative changes in the NEI-VFQ-25 scores in our study after controlling for confounders. Most important changes were observed in subscales, such as general vision (-6.46 points), mental health (-10.19 points), role difficulty (-6.90 points), and driving (-10.43 points). Unemployment and the development of long-term complications, such as nephropathy, were also associated with negative changes in some NEI-VFQ-25 subscale scores. However, changes in diabetic retinopathy status were not related to changes in any subscale after 10 years.Change in visual acuity was the most important factor associated with changes in vision-related quality of life scores in individuals with type 1 diabetes during a 10-year period. Our findings support the necessity of close follow-up of individuals with type 1 diabetes to avoid development of long-term complications and vision loss to improve quality of life.
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