产科
糖尿病
生物标志物
怀孕
胎龄
小于胎龄
接收机工作特性
作者
Ahmed M. Maged,Ghada Abdel Fattah Moety,Walaa Ahmed Mostafa,Dalia Ahmed Hamed
标识
DOI:10.3109/14767058.2013.850489
摘要
AbstractObjective: To study various biomarkers in prediction of gestational diabetes mellitus (GDM).Patients and methods: Prospective observational study included 400 pregnant women. Maternal serum sex hormone binding globulin (SHBG), high-sensitive C-reactive protein (hs-CRP), uric acid, creatinine and albumin were measured before 15 weeks of gestation. Patients were followed-up for development of GDM.Results: A total of 269 women were eligible for analysis. GDM complicated 27 (10.03%) of pregnancies. Hs-CRP levels were significantly higher and SHBG levels were significantly lower among women who subsequently developed GDM compared with normoglycemics. Uric acid, albumin and creatinine levels were not significantly different between both groups. For prediction of GDM, hs-CRP at a cutoff value of 2.55 mg/l showed a sensitivity and a specificity of 89% and 55%, respectively. SHBG at a cutoff value of 211.5 nmol/l showed a sensitivity and a specificity of 85% and 37%, respectively. Low SHBG with high hs-CRP...
科研通智能强力驱动
Strongly Powered by AbleSci AI