Frailty as a predictor of clinical problems and events that require elderly patients with heart failure to use health resources

多药 医学 心力衰竭 回顾性队列研究 观察研究 老年病科 队列 内科学 重症监护医学 急诊医学 精神科
作者
FJ. Flores-Álvarez,Alba Sillero-Herrera,J. Cuesta-Gaviño,M.L. Fernández-Sánchez,J. Vega-Sánchez,JL. López-Fe,Fernando Gamboa,D. Utrilla-Ayala,Alfonso Aguirre-Palacio,Ernesto de Villar-Conde,Salvador Vergara-López
出处
期刊:Archives of Gerontology and Geriatrics [Elsevier BV]
卷期号:101: 104698-104698 被引量:6
标识
DOI:10.1016/j.archger.2022.104698
摘要

The clinical management of elderly patients with heart failure (HF) is not firmly established. Decision-making should be individualized depending on the biological deterioration of each patient, from aggressive management to a palliative approach. Frailty can serve as the basis for this comprehensive individualized management. Our objective was to evaluate the importance of the main clinical problems, as well as the events that required the use of health resources, based the degree of frailty, in elderly patients with HF.Retrospective observational cohort study. Frailty was defined according to the deficit accumulation construct. A total of 546 patients hospitalized for acute HF were included. The median age (Q1-Q3) was 82 (78-86) years. A total of 454 patients (83%) showed some degree of frailty: 221 (48.7%) mild, 207 (45.6%) moderate and 26 (5.7%) advanced. There was a significant tendency towards polypharmacy from no to severe frailty. Hospital events were recorded for 4 (1-6) patients with mild frailty, 4 (2-6) patients with moderate frailty and 2 ((1-4) patients with advanced frailty (p = 0.045). A total of 204 patients (37.4%) died during follow-up. The median time to death was 11.4 (4-16.8), 6.7 (3.3-11.6), 6.5 (3.4-12.2) and 4.1 (0.8-7.7) months for patients with no, mild, moderate, or advanced frailty, respectively (p = 0.006).Frailty due to deficit accumulation is a good predictor of clinical problems and events that require the use of health resources; therefore, it can serve as a basis for the management of HF in the elderly.

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