单克隆抗体
抗体
欧西里斯
单克隆
融合蛋白
化学
计算生物学
免疫学
医学
生物
生物化学
重组DNA
植物
基因
出处
期刊:Humana Press eBooks
[Humana Press]
日期:2000-01-01
卷期号:: 281-288
被引量:3
标识
DOI:10.1385/1-59259-076-4:281
摘要
A major breakthrough in immunology came with the discovery that large amounts of relatively pure monoclonal antibodies (mAbs) could be prepared from the fusion of B cells (secreting the relevant mAb) with a nonsecreting myeloma cell line (). Since then mAbs have become a central tool for researchers, enabling them to investigate previously unknown molecules. More recently mAbs have also gained an important role in medicine, e.g., in helping to prevent allograft rejection and in the treatment of digoxin poisoning.
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