化学
筑地反应
丙二酸
钯
催化作用
配体(生物化学)
乙二醇
烯丙基重排
烷基化
高分子化学
有机化学
组合化学
药物化学
生物化学
受体
作者
Marco Bandini,Maurizio Benaglia,Tommaso Quinto,Simona Tommasi,Achille Umani‐Ronchi
标识
DOI:10.1002/adsc.200606125
摘要
Abstract A new class of chiral C 1 ‐symmetrical diamino‐oligothiophene ligands easy‐grafted on a soluble polymeric support (MeOPEG 5000 ) is described. The diamines were found to be effective promoting agents for the [Pd(0)]‐catalysed asymmetric allylic alkylation (AAA) of dimethyl malonate in high yields and excellent enantioselectivity ( ee up to 99 %). The supported chiral ligand was readily recovered by precipitation and filtration was recycled up to three times without an appreciable loss in activity. The recycle of the organometallic catalytic system was also investigated.
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