乳腺癌
生物
新辅助治疗
癌症
化疗
肿瘤科
DNA修复
外显子组
癌症研究
外显子组测序
突变
内科学
医学
遗传学
基因
作者
Ryan L. Powles,Vikram B. Wali,Xiaotong Li,William E. Barlow,Zeina Nahleh,Alastair M. Thompson,Andrew K. Godwin,Christos Hatzis,Lajos Pusztai
标识
DOI:10.1158/1078-0432.ccr-19-2405
摘要
We performed whole-exome sequencing (WES) of pre- and posttreatment cancer tissues to assess the somatic mutation landscape of tumors before and after neoadjuvant taxane and anthracycline chemotherapy with or without bevacizumab.
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