眼内容剜除术(眼科)
剜除术
医学
眼内炎
外科
回顾性队列研究
视力
玻璃体切除术
眼科
病理
替代医学
作者
Meleha Ahmad,Rupin Parikh,Anam Akhlaq,Tejus Pradeep,Mark P. Breazzano,Roxana Fu
出处
期刊:Orbit
[Informa]
日期:2022-07-20
卷期号:42 (3): 279-289
标识
DOI:10.1080/01676830.2022.2097699
摘要
Purpose To identify clinical risk factors for enucleation or evisceration in patients with endophthalmitis at an academic institution.Methods A retrospective review of patients diagnosed with endophthalmitis at Wilmer Eye Institute from 2010 to 2019 was conducted. Clinical characteristics, including demographics, cause for endophthalmitis, microbial culture results, salvaging procedures and surgical intervention were recorded. In patients who underwent enucleation or evisceration, type of surgery and placement of a primary implant were recorded. Chi-squared, Student’s t-tests and multivariate analysis were used to identify clinical factors that predicted enucleation or evisceration.Results Two hundred and fifty three patients treated for endophthalmitis over the study period were identified, of which 25 (9.88%) underwent enucleation or evisceration. Risk factors for enucleation or evisceration included poor presenting visual acuity (OR 7.86, CI: 2.26, 27.3), high presenting intraocular pressure (OR 1.07, CI: 1.03, 1.12), presence of relative afferent pupillary defect (OR 3.69, CI: 1.20, 11.37) and positive vitreous culture for methicillin-resistant staphylococcus aureus (MRSA) (OR 18.3, CI: 1.54, 219.2) on multivariate analysis. Patients undergoing enucleation or evisceration were also more likely to have trauma, corneal ulcer or combined causes for endophthalmitis and underwent fewer salvaging surgical and procedural interventions. There were no significant differences in characteristics of those receiving enucleation versus evisceration in our cohort.Conclusion Patients with endophthalmitis who underwent enucleation or evisceration had more severe disease on presentation compared to those treated with eye sparing therapy. Presenting clinical characteristics may have a role in triage and management decisions for patients presenting with severe endophthalmitis.
科研通智能强力驱动
Strongly Powered by AbleSci AI