Detection rate and risk factors analysis of motoric cognitive risk syndrome

Objective To investigate the detection rate of motoric cognitive risk syndrome(MCR)and explore the possible risk factors. Methods A total of 429 elderly patients from geriatric department of Zhejiang Hospital from October 2014 to September 2018 were recruited in the cross-sectional study.General information and functional assessment including fall history, self-reported visual impairment and hearing impairment, depressive symptom, cognitive function and gait speed were collected.Patients with MCR were screened out according to the MCR diagnostic criteria.Multiple logistic regression analysis was used to analyze the associated risk factors. Results Seventeen patients(4.0%)met the MCR diagnostic criteria.The proportions of obesity, polypharmacy, cerebral vascular diseases, self-reported hearing impairment, depressive symptoms and slow gait were higher in MCR patients than in non-MCR patients(P<0.05). Compared with non-MCR patients, MCR patients had lower mini mental state examination(MMSE)scores(P<0.01). After adjusting for associated confounding factors, multiple logistic regression analysis showed obesity(OR=3.74, 95%CI: 1.14-12.23, P<0.05)and depressive symptoms(OR=5.79, 95%CI: 1.76-19.06, P<0.01)were risk factors for MCR. Conclusions MCR is not uncommon in elderly patients.Obesity and depressive symptoms are closely associated with an increased risk of MCR. Key words: Cognition; Gait; Dementia; Risk factors