心理学
走/不走
听力学
执行职能
注意缺陷多动障碍
工作记忆
任务(项目管理)
反应抑制
顺利追击
发展心理学
眼球运动
认知
神经科学
精神科
医学
经济
管理
机器学习
计算机科学
作者
F. Xavier Castellanos,Farshad Fani Marvasti,Julie L. Ducharme,James M. Walter,Margaret E. Israel,Amy L. Krain,Candela Pavlovsky,Daniel W. Hommer
标识
DOI:10.1097/00004583-200005000-00019
摘要
To assess executive function in girls with attention-deficit/hyperactivity disorder (ADHD) using oculomotor tasks as possible trait markers for neurobiological studies.Thirty-two girls aged 6 to 13 years with DSM-IV ADHD and 20 age-matched, normal control girls were tested on a variety of oculomotor tasks requiring attention, working memory, and response inhibition, which included smooth pursuit, delayed response, and go-no go tasks.Girls with ADHD performed the delayed response task correctly on 32% of trials as measured by number of memory-guided saccades, in contrast to 62% of trials for control subjects (p = .0009). Patients made twice as many commission errors to no go stimuli (p = .0001) and 3 times as many intrusion errors (saccades in the absence of go or no go stimuli; p = .004) during the go-no go task compared with controls. Smooth pursuit performance was statistically equivalent across subject groups. Repeated testing in a subgroup of 15 patients revealed substantial practice effects on go-no go performance.The data confirm that girls with ADHD exhibit impairments in executive function, as has been reported in boys, implying a similar pathophysiology of ADHD in both sexes. However, practice effects may limit the utility of the oculomotor go-no go task for some neurobiological studies.
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