细胞因子
CD8型
过继性细胞移植
生物
免疫疗法
免疫系统
白细胞介素2
细胞生物学
免疫学
癌症免疫疗法
癌症研究
T细胞
细胞毒性T细胞
体外
生物化学
作者
Jonathan T. Sockolosky,Eleonora Trotta,Giulia Parisi,Lora K. Picton,Leon Su,Alan Le,Akanksha Chhabra,Stephanie Silveria,Benson M. George,Indigo C. King,Matthew Tiffany,Kevin M. Jude,Leah V. Sibener,David Baker,Judith A. Shizuru,Antoni Ribas,Jeffrey A. Bluestone,K. Christopher García
出处
期刊:Science
[American Association for the Advancement of Science]
日期:2018-03-01
卷期号:359 (6379): 1037-1042
被引量:364
标识
DOI:10.1126/science.aar3246
摘要
IL-2 pairs were efficacious in a preclinical mouse cancer model of adoptive cell therapy and may therefore represent a synthetic approach to achieving selective potentiation of engineered cells.
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