自身免疫
CD19
免疫学
疾病
肌炎
生物
自身免疫性疾病
癌症
多发性硬化
癌症研究
医学
抗体
内科学
遗传学
解剖
作者
Heather M. Sosnoski,Avery D. Posey
标识
DOI:10.1016/j.stem.2024.03.006
摘要
Anti-CD19 CAR T cells were among the last decade's scientific breakthroughs, achieving remarkable remissions in patients with B cell leukemias and lymphomas. Now, the engineered cell therapies are traversing disease indications into autoimmunity and resolving disease symptoms in patients with systemic lupus erythematosus (SLE), idiopathic inflammatory myositis, and systemic sclerosis.1.
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