艾地明
化学
烷基化
自动氧化
催化作用
有机化学
反应条件
作者
Jie Zhang,Xiaolan Li,Lieqiang Liao,Haidong Liu,Haiqing Luo
标识
DOI:10.1002/adsc.202301093
摘要
Abstract The air mediated radical alkylation of cyclic aldimines via autoxidation of alkylboronic acids has been realized under mild reaction conditions. By simply heating cyclic aldimines with alkylboronic acid using air as sole oxidant, this protocol provides a catalyst‐free access to a variety of alkylated cyclic aldimines with 21–91% yields. Preliminary mechanistic studies suggest that a radical pathway might be involved in the reaction.
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