A Cyclohexyl-1,2-diamine-Derived Bis(binaphthyl) Macrocycle: Enhanced Sensitivity and Enantioselectivity in the Fluorescent Recognition of Mandelic Acid

Optically active cyclohexanediamine-based bis(binaphthyl) macrocyle (S)-1 shows a highly sensitive and enantioselective fluorescent recognition of mandelic acid: That is, while the R enantiomer of mandelic acid causes little change in the fluorescence of the macrocycle, the S enantiomer enhances the fluorescence by over 20-fold.