Physiology
Brown fat can release energy from food as heat instead of storing it and could thus help in battling obesity. Li et al. found that after a meal, brown fat in mice was stimulated to increase thermogenesis by direct action of the gut hormone secretin. The heat produced may be detected by the brain and thus induce a sense of satiety. This signaling relay may increase energy expenditure and decrease appetite, making it a potential target for therapies that attempt to control obesity.
Cell 175 , 1561 (2018).