Cranial diabetes insipidus with pituitary stalk lesions

Cranial diabetes insipidus (CDI) is the deficiency of vasopressin.CDI is rarely resulted from a pituitary stalk lesion; these cases represent a clinical conundrum due to the differing clinical presentations and aetiologies.We present a series of three cases of CDI arising from pituitary stalk lesions/thickenings that highlight both the symptomatic features and multiple aetiologies of this condition.