转铁蛋白
膳食铁
化学
吸收(声学)
内科学
医学
缺铁
生物化学
贫血
材料科学
复合材料
作者
Sofiya Tsyplenkova,Edouard Charlebois,Carine Fillebeen,Kostas Pantopoulos
出处
期刊:Blood
[American Society of Hematology]
日期:2024-03-25
标识
DOI:10.1182/blood.2023022916
摘要
Intravenous injection of excess apo-transferrin enhances dietary iron absorption in mice, and triggers accumulation of plasma non-transferrin bound iron (NTBI). Injected fluorescent-labeled transferrin colocalizes with lamina propria macrophages, consistent with the recently proposed iron absorption checkpoint involving macrophage-mediated transferrin degradation.
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