Self-Propelled Peg-Fe3o4@Mno2 Janus Magnetic Nanorobots as Enzyme-Like for Dynamic Detection of Gsh and Efficient Degradation of Tch

A novel magnetically controllable Janus nanorobot is designed to realize dynamic colorimetric detection of glutathione (GSH) and degradation of tetracycline hydrochloride (TCH) by using calcined manganese (Ⅱ) acetate modified Fe3O4@PAA to construct asymmetric MnO2 template as the intelligent platform. The obtained PEG-Fe3O4@MnO2 magnetic Janus nanorobots (P-FM JMNs) have a unique asymmetric structure and could be driven by oxygen (O2) bubbles generated by catalytic decomposition of H2O2 at a maximum speed of 95.2 μm/s in the presence of 5 wt% H2O2. Combining the advantages of self-propelled motion, superior enzyme-like activity and unique Janus asymmetric structure, P-FM JMN as an effective nanocarrier was established for dynamic sensitive colorimetric detection of GSH with a detection limit of 0.0898 μM and rapid degradation of TCH via excellent Fenton-like activity in water. Moreover, the nanorobots can achieve effective magnetic recovery to reduce environmental pollution. The magnetic Janus nanorobots provide a new insight into the field of environmental remediation.