染色体易位
核仁
生物
分区(防火)
异位表达
遗传学
基因
基因座(遗传学)
转录因子
细胞生物学
细胞质
酶
生物化学
作者
О.В. Яровая,Е.С. Юдинкова,S. V. Razin,Е.С. Васецкий
标识
DOI:10.7868/s0026898418020040
摘要
The review summarizes the results from a series of studies focusing on the role that the nucleolus plays in maturation of the IGH locus and the choice of its partner genes in leukemia-associated translocations. The role of nuclear compartmentalization and nuclear localization of translocated oncogenes in ectopic activation of their transcription is discussed.
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