[Changing trend regarding the burden on cerebrovascular diseases between 1990 and 2016 in China].

Objectives: To analyze the status quo and trends on the burden of cerebrovascular diseases between 1990 and 2016 in China. Methods: Morbidity mortality, years of life lost (YLL), years of lived with disability (YLD) and disability-adjusted life year (DALY) related to cerebrovascular diseases between 1990 and 2016, were collated and analyzed, according to the results of the Global Burden of Diseases Study 2016 (GBD 2016). Numbers on incidence and morbidity were used to assess the incidence of diseases, while the numbers of death and mortality were used to assess the death of diseases. Years of life lost due to premature death (YLL), years lost due to disability (YLD) and disability-adjusted life year (DALY) were used to assess the burden of diseases. Changing trend on the burden of cerebrovascular disease from 1990 to 2016 was also analyzed. Results: In 2016 and 1990, the numbers of new cases/morbidity and the number of deaths/mortality on cerebrovascular diseases in the country showed an upward trend. Rates regarding YLL and DALY on cerebrovascular diseases remained stable from 1990 to 2016, however, the YLD rate showed a slow upward trend. The changing rate of DALY was mainly influenced by YLL. Both DALY and YLL crude rates in males showed a slow upward trend, with the highest DALY rate appearing in the ≥70 age group. Disease burden on males was heavier than that of the females and in the 50-60 age group, which taking the largest proportion. As for the composition in DALY, YLL appearing much larger than YLD and slowly increasing. Analysis on the subtypes of diseases, proportions of YLL and DALY in hemorrhagic stroke were greater than that in ischemic stroke while the proportion of YLD in ischemic stroke was in the opposite. Conclusions: The burden of disease on cerebrovascular diseases remained heavy and the differences appeared in age, gender and subtypes of diseases. Our findings called for the adoption of measures including screening, intervention and rehabilitation to be taken on target populations, in order to reduce the burden on both individuals and the society.目的： 分析1990－2016年脑血管病在我国造成的疾病负担现状和趋势，为疾病预防和控制政策提供线索。 方法： 应用2016年全球疾病负担研究的结果，采用死亡人数和死亡率评估死亡水平；采用发病人数和发病率评估发病水平；采用伤残损失寿命年（YLD）、过早死亡损失寿命年（YLL）和伤残调整寿命年（DALY）来评价我国不同年份、年龄、性别、疾病亚型的脑血管病疾病负担情况，并分析1990－2016年脑血管病的疾病负担的变化趋势。 结果： 与1990年相比，2016年我国脑血管病的发病人数（率）和死亡人数（率）都呈现上升趋势。1990－2016年脑血管病的YLL率、DALY率总体保持平稳，YLD率呈缓慢上升趋势，DALY率的变化主要来源于YLL率的变化；男性DALY、YLL粗率总体呈现缓慢上升趋势，≥70岁组DALY率最大；各指标性别、年龄组构成中，男性疾病负担较女性重，50~岁组所占比例最大；分性别、年龄组的DALY构成中，均为YLL所占比例远远大于YLD，YLD呈缓慢上升趋势；疾病亚型构成分析显示，出血性卒中的YLL和DALY占比大于缺血性卒中，缺血性卒中YLD占比大于出血性卒中。 结论： 脑血管病的疾病负担较重，其在年龄、性别、疾病亚型等方面均存在差异，需采取针对性的筛查、干预、康复等措施，减轻其对个人及社会造成的负担。.